Mirtazapine EP IMpurity A (USP RC B) - Names and Identifiers
Name | Mirtazapine N-Oxide
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Synonyms | Mirtazapine N-Oxide Mirtazapine Impurity A Mirtazapine EP IMpurity A Mirtazapine Related CoMpound B Mirtazapine EP IMpurity A (USP RC B) 1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-α]pyrido[2,3-c][2]benzazepine 2-Oxide 1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-Oxide Mirtazapine Related Compound B (25 mg) (1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-oxide monohydrate)
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CAS | 155172-12-6
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Mirtazapine EP IMpurity A (USP RC B) - Physico-chemical Properties
Molecular Formula | C17H19N3O
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Molar Mass | 281.35 |
Melting Point | 185-187°C |
Solubility | Chloroform (Slightly, Heated), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Yellow to Pale Beige |
pKa | 5.17±0.20(Predicted) |
Storage Condition | Hygroscopic, Store under Inert atmosphere -20°C Freezer |
Mirtazapine EP IMpurity A (USP RC B) - Risk and Safety
Mirtazapine EP IMpurity A (USP RC B) - Introduction
Mirtazapine N-Oxide, also known as Mirtazapine N-Oxide, is one of the main metabolites of Mirtazapine. The following is a description of some of the properties, uses, methods and safety information of Mirtazapine N-Oxide:
1. Nature:
Mirtazapine N-Oxide is white crystalline powder with good chemical stability. It is hydrophobic, poorly soluble, and soluble in organic solvents such as ethanol and dichloromethane.
2. Use:
The Mirtazapine N-Oxide is mainly used as a reference compound for research purposes, for the Study of Mirtazapine (a commonly used antidepressant) and its metabolic pathways.
3. Preparation method:
Mirtazapine N-Oxide is usually transformed from Mirtazapine in vivo through in vitro metabolic studies under metabolic conditions set by human plasma or animal laboratories.
4. Safety Information:
There are limited studies on the toxicity and safety of Mirtazapine N-Oxide, so there is no specific safety information and risk assessment data in the pharmaceutical and medical fields. In general, when using or handling Mirtazapine N-Oxide, appropriate laboratory safety practices and precautions should be taken, such as wearing gloves, wearing lab clothes, and avoiding inhalation or contact. In addition, further research and evaluation are needed to understand its toxicity and safety in humans. Use in accordance with relevant chemical handling and handling specifications.
Please note that the above information is for reference only. The specific use or handling of Mirtazapine N-Oxide should refer to relevant scientific literature and safety guidelines, and follow laws and regulations.
Last Update:2024-04-09 20:52:54